I forgot to mention that both games are free to play (and have paid subscriber benefits). In case you wanted to try with them.

swtor.com
wurmonline.com

I can only name two off of the top of my head. I am also 90%+ certain that they have done it on purpose. Additionally, if you use a screen sharing program and then run the macro, the clicks work just fine and register because they are working in the screen sharing program which then sends it to the ...

Some programs ignore mouse clicks (and keyboard commands) from macroscheduler but real mouse clicks work fine.

I have not found any solution yet that can simulate a "real" mouse click using this program.